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Medications & Supplements

  • Midazolam is a benzodiazepine used for its sedative, anti-anxiety, and muscle relaxant properties. It is primarily used as a sedative before surgery and to stop seizures. It is used “off label” or “extra label” in animals. This medication is a controlled substance primarily given via injection by your veterinary team, though it may be prescribed to your pet for intranasal or intrarectal administration at home.

  • Milbemycin otic (brand name MilbeMite® Otic solution) is an antiparasitic used in the treatment of ear mite infestations in cats and kittens four weeks of age or older. Milbemycin otic comes in liquid drop form (in pre-measured ampules).

  • Milbemycin oxime (brand name: Interceptor®) is a heartworm disease preventive and treats internal parasites (e.g., hookworms and roundworms) in dogs and cats. It is also found in combination products with other drugs. It is also used off label to treat infestations in dogs. Milbemycin is given by mouth with a flavored oral tablet. At regular doses, milbemycin is well-tolerated; when used at higher doses for treating mites, side effects have been observed. Some breeds of dogs (e.g., collies, sheepdogs, and collie- or sheepdog-cross breeds) are more sensitive to milbemycin than others; your veterinarian will advise you on the safety of milbemycin use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Milbemycin oxime + lufenuron (brand name Sentinel®) is a heartworm disease preventive that also treats internal parasites (e.g., whipworms, hookworms, and roundworms) and controls flea populations in dogs. Milbemycin oxime + lufenuron is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated; when used off-label at higher doses for treating mites, side effects have been observed. Your veterinarian will advise you on the safety of milbemycin oxime + lufenuron use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Milbemycin oxime + lufenuron + praziquantel (brand name Sentinel Spectrum®) is a heartworm disease preventive that also treats certain internal parasites and controls fleas in dogs. This combination medication is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated. Certain dog breeds are more sensitive to milbemycin than others; your veterinarian will advise you on the safety of milbemycin use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Milbemycin oxime + praziquantel (brand name: Interceptor Plus®) is a heartworm disease preventive that also controls tapeworms, hookworms, roundworms, and whipworms in dogs. It is given by mouth as a flavored chew tablet and must be given with a meal to ensure adequate absorption. At prescribed doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of this combination product’s use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Milbemycin oxime + spinosad (brand name: Trifexis®) is a heartworm disease preventive that also controls hookworms, roundworms, whipworms, and fleas in dogs. Milbemycin oxime + spinosad is given by mouth as a flavored chew tablet. At prescribed doses, this medication is well-tolerated. Your veterinarian will advise you on the safety of this product’s use in your dog. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately.

  • Silymarin is an over-the-counter nutritional supplement that is used off-label and is given by mouth to treat liver and cancer conditions. Give as directed. Side effects are uncommon but may include vomiting or diarrhea. Do not use it in pets that are allergic to it. If a negative reaction occurs, please call the veterinary office.

  • Mirtazapine (brand name: Mirataz®) is given by mouth or is applied to the skin and is used to treat weight loss in cats and is used off-label to treat inappetence, nausea, and vomiting in cats and dogs. Give as directed. The most common side effects include vocalization, restlessness, vomiting, incoordination, or trembling. Do not use it in pets that are allergic to it or that have recently used an MAOI. If a negative reaction occurs, call your veterinarian.

  • Molidustat (brand name Varenzin-CAI) is a medication used to treat anemia (low red blood cell number) in cats with chronic kidney disease. Molidustat helps increase red blood cell production. It is conditionally approved for use in cats only. It comes in liquid suspension form.