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Medications & Supplements

  • Phytosphingosine topical (brand names Douxo®, SkinGuard®) is an anti-inflammatory agent, with antibacterial and antifungal properties. It is used in cats and dogs to help relieve itching in certain skin conditions and help restore the skin barrier. Phytosphingosine topical may be part of a combination product.

  • Pimobendan (brand name: Vetmedin®) is a medication given by mouth as a tablet or liquid, used to treat congestive heart failure in dogs. Its use in cats is off label. The most common side effects include decreased appetite and diarrhea. This medication should not be used in dogs with certain heart conditions, and it should be used with caution in pets with metabolic disease or pets that are young, pregnant, breeding, or lactating. If a negative reaction occurs, call the veterinary office.

  • Piroxicam (brand name: Feldene) is given by mouth in the form of a capsule to treat pain and some types of cancer in dogs. Do not use this medication in pets that are allergic to it, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, please call your veterinary office.

  • Polysulfated glycosaminoglycan (Adequan®) is an injectable disease-modifying osteoarthritis drug (DMOAD) used to treat non-infectious and traumatic arthritis in dogs. It is also used off-label in cats and small mammals. If administering this medication at home, follow your veterinarian’s instructions and dispose of the needle and syringe appropriately. Side effects are rare when given according to label recommendations and at prescribed intervals. Do not use this medication in pets with a known hypersensitivity to it, in pets with known or suspected bleeding disorders or immune-mediated arthritis, or in pets with severe kidney or liver disorders.

  • Povidone iodine topical (brand names Vetadine®, Poviderm®, Povidine®, others) is a topical antiseptic used on the skin prior to surgery and in first aid treatments for cats and dogs. It has been used in aquatic species and reptiles to treat fungal infections and wounds. Povidone iodine topical comes in liquid solution, gel, ointment, scrub, shampoo, and spray forms.

  • Pradofloxacin (brand name Veraflox®) is an antimicrobial medication used to treat bacterial infections. It is used to treat skin, urinary tract, and respiratory tract infections in cats. Pradofloxacin is approved for use in dogs in certain countries. It is used "off label" or "extra label" to treat other types of infections in cats and some types of infections in dogs.

  • Praziquantel is given on and off label and by mouth or injection to treat various internal parasites. Side effects are uncommon but may include lack of appetite, vomiting, diarrhea, drooling, or tiredness. Do not use in pets that are allergic to it, in puppies less than 3 weeks old, or kittens less than 6 weeks old. If a negative reaction occurs, please call your veterinary office.

  • Praziquantel/pyrantel pamoate (brand name Drontal) is an oral antiparasitic drug used to treat and control hookworms, roundworms, and tapeworms in cats and kittens that are at least 8 weeks of age and weigh at least 0.9 kg (2 lb), and in dogs and puppies that are at least 12 weeks of age and weigh at least 2.7 kg (6 lb). Praziquantel/pyrantel pamoate comes in tablet form.

  • Praziquantel/pyrantel pamoate/febantel (brand name Drontal Plus) is an oral antiparasitic drug used to treat and control hookworms, roundworms, whipworms, and tapeworms in dogs and puppies that are at least 3 weeks of age and weigh at least 0.9 kg (2 lb). Praziquantel/pyrantel pamoate/febantel comes in tablet form. It may be used “off label” or “extra label” in other species (not recommended in cats) for certain conditions.

  • Prazosin is given by mouth and is used to reduce urinary sphincter tone to relax the bladder and allow easier urination in dogs and cats. It may also be used as a treatment for congestive heart failure, systemic hypertension, or pulmonary hypertension in dogs. Give as directed. Common side effects include lethargy, vomiting, diarrhea, nausea, and constipation. This medication should be used with caution in pets with kidney disease or other conditions that cause low blood pressure, as well as in MDR1-positive dogs. If a negative reaction occurs, contact your veterinarian.