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A luxating patella is a kneecap that moves out of its normal location, causing an affected dog to skip or hop on three legs. Many toy or small breed dogs, including the Maltese, Chihuahua, French Poodle, and Bichon Frise, have a genetic predisposition for a luxating patella. Surgery should be performed to prevent the development of arthritis or another knee injury.
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Lymphocytic plasmacytic gastroenteritis is a form of inflammatory bowel disease. While the exact cause is not known, it is possible that the intestinal bacteria themselves may be involved in stimulating the immune response. Signs include diarrhea, vomiting, loss of appetite, weight loss, and blood in the stool/vomit. Treatment may include nutrition management, immunosuppressive medications, and dietary supplementation of cobalamin, prebiotics, and probiotics.
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Lymphocytic plasmacytic gastroenteritis is a form of inflammatory bowel disease. While the exact cause is not known, it is possible that the intestinal bacteria themselves may be involved in stimulating the immune response. Treatment may include nutrition management, immunosuppressive medications, and dietary supplementation of cobalamin, prebiotics, and probiotics.
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Lymphoma is a cancer of the lymphocytes. Lymphocytes are cells that are involved in the immune system. Feline lymphoma most commonly affects the intestines; therefore, clinical signs of lymphoma are often similar to other intestinal diseases. Diagnosing lymphoma requires finding cancerous cells on microscopic examination. This cancer cannot be prevented, but the likelihood of a cat developing lymphoma can be decreased by preventing feline leukemia virus infection.
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Lymphoma is a cancer of the lymph nodes and lymphatic system. This cancer may be localized to one particular region, or may spread throughout the entire body. Lymphoma is a relatively common cancer, accounting for 15-20% of new cancer diagnoses in dogs. The prognosis for lymphoma varies, depending on various characteristics that can only be determined by specialized testing.
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Lysosomal storage diseases are a rare collection of conditions that are inherited. Many of them are more prevalent in certain breeds and are seen in the first few months of life. Clinical signs vary depending on the type of disease, but commonly include failure to thrive, incoordination, vision loss, and seizure. Prognosis is usually poor for long-term survival.
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Bacterial overgrowth is a condition of the small intestine resulting in increased numbers of bowel bacteria. The major concern with bacterial overgrowth is the development of a condition called small intestinal bacterial overgrowth. The bacteria cause damage to the surface of the bowel so digested food cannot be absorbed resulting in malabsorption of nutrients. Malabsorption and SIBO both result in diarrhea but with bacterial overgrowth the diarrhea is chronic. Many cases respond to long term antibiotics.
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Mast cells are a type of white blood cell that plays a large role in allergic response through degranulation. Mast cell tumors (MCT) can occur in the skin, spleen, or gastrointestinal tract of cats. Their cause is unknown; however, many affected cats show a genetic mutation in the KIT protein involved in replication and cell division. Cutaneous MCTs most often appear as hard pale/white plaques or nodules, often around the head and they may be itchy. Splenic MCTs cause decreased appetite, weight loss, and vomiting. Intestinal MCTs may cause GI upset and bloody stools, and a mass may be palpable. Diagnosis is typically achieved via fine needle aspirate although histopathology can be used. Treatment usually requires surgical removal of the masses or the spleen. Sometimes, chemotherapy or radiation is needed.
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Mast cell tumors are most common in the skin of dogs and may appear red, ulcerated, or swollen. They can be itchy and can fluctuate in size. Tumors can range from lower-grade, with minimal spread, to higher-grade, with a high risk of local invasion. Treatment usually involves surgical removal and may require supportive treatment including chemotherapy, radiation therapy, and therapy to target the mutation that instigated the tumor.
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Masticatory muscle myositis (MMM) is an immune system disorder in which the dog's immune system identifies the dog's own muscle tissue as foreign and attacks it.