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Cerebrospinal fluid is a clear, colorless fluid found in the brain and spinal cord. The collection of CSF is usually indicated when a pet shows clinical signs, such as seizures, incoordination, circling behavior, and neck or back pain, when no obvious cause is known. The veterinary pathologist will evaluate the sample for a total nucleated cell count, a red blood cell count, a total protein determination, and a concentration of the cells in the sample. The presence of bacteria or fungal organisms may be detected along with increased numbers of inflammatory cells, leading to a diagnosis of bacterial or fungal infection. Neoplastic cells may also be found, indicating an underlying tumor within the brain or spinal cord.
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The intervertebral discs allow movement in the spine and act as shock absorbers between the vertebrae. If the disc degenerates or is damaged in some way, the disc may bulge and put pressure on the spinal cord and/or the roots of the spinal nerves that come off the sides of the spinal cord. This pressure can cause symptoms ranging from severe pain to weakness to paralysis. There are several breeds that experience a higher frequency of the condition. The severity of a dog’s clinical signs depends upon several factors. Conservative management with pain relievers and anti-inflammatory medication is recommended with a gradual onset of clinical signs or when clinical signs are limited to pain and/or a mildly wobbly gait. Surgery is recommended when there are repeated episodes of neck pain, when neck pain is severe, when there are severe nervous system deficits, or when the dog has not responded to conservative treatment.
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Cervical vertebral instability (wobbler syndrome) is caused by compression of the spinal cord, usually at the base of the neck. Although the spinal cord compression occurs in the neck, the hind legs are often affected first. In severe cases, the dog may suddenly develop total paralysis of all four limbs. The condition is most prevalent in Great Danes and Doberman Pinschers. Most pets enjoy a relatively normal lifestyle following surgery.
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A cesarean section is a surgery to remove kittens from the uterus and is most commonly performed as an emergency procedure when there is difficulty with natural birth. During the immediate recovery period, the mother and kittens must be closely monitored and begin eating/nursing within a few hours. If you have any concerns about their health, you should immediately have your veterinarian examine the kittens and their mother.
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Cetirizine is given by mouth and is used off-label to treat and prevent pruritus (itching) associated with atopic dermatitis, urticaria (hives), and insect bite reactions in cats and dogs. Give as directed. Side effects are uncommon but may include vomiting and increased salivation. Do not use it in pets that are allergic to it or hydroxyzine. If a negative reaction occurs, contact your veterinarian.
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This handout summarizes Chagas disease in dogs. Caused by a protozoal parasite called Trypanosoma cruzi, it is spread by the bite of infected insects or ingestion of infected insects and rodents. The clinical signs of the condition, along with its treatment, prevention, and risk to human health are outlined.
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Chediak-Higashi Syndrome is a rare genetic disease of smoke-blue Persian cats. The condition affects how the body processes waste products, resulting in changes within the body’s cells and leading to abnormal pigmentation of the skin and coat. The condition can lead to eye abnormalities and problems with blood clotting, but most cats can have a normal lifespan with careful health monitoring.
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A chemodectoma is a type of tumor made up of chemoreceptor cells. Chemoreceptor cells detect chemical changes in the body and respond by regulating chemical or physical processes. These tumors are most often seen along one of the carotid arteries and the aorta. Brachycephalic breeds are more predisposed to these types of tumors, though they may occur in any dog breed. These tumors are usually locally aggressive, however, there are rare cases of metastasis to other organs, including the lungs, lymph nodes, and bone.
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Chemotherapy is the therapeutic use of chemical agents to destroy or inhibit the growth and division of cancer cells. Usually, chemotherapy is used when tumors are widespread or when there is significant or immediate risk of spread from the primary location. It is often used following the surgical removal of tumors. In some cases, chemotherapy is started prior to surgery. The side effects of chemotherapy are related to the effects of chemotherapy on normal -as well as cancerous- cells. The principal goal of cancer care in pets is to provide cancer control without reducing quality of life.
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Chemotherapy drugs are used to treat cancer and other conditions in people because they target and kill rapidly dividing neoplastic (cancer) cells and other cells. They are primarily used as anti-cancer agents but may also provide benefits for a variety of auto-immune disorders and organ transplant recipients as immunosuppressive agents.